abstract：:The level of endogenous nerve growth factor (NGF) in rat sciatic nerve was determined using a highly sensitive two-site enzyme immunoassay. After crushing this nerve NGF accumulated linearly distal to the crush during the first 12 h to reach levels 13-fold higher than in the uncrushed contralateral side. In contrast, ...

journal_title：Neuroscience letters

authors： Korsching S,Thoenen H

更新日期：1983-08-19 00:00:00

abstract：:Convergence of cardiac and cutaneous afferents onto neurons in the dorsal horn of the spinal cord was demonstrated in the cat. Responses of neurons to cutaneous stimulation revealed that they were either nociceptive specific (NS) or wide dynamic range (WDR) neurons. NS neurons were located in lamina I and outer zone o...

journal_title：Neuroscience letters

authors： Takahashi M,Yokota T

更新日期：1983-08-08 00:00:00

abstract：:The three tracers horseradish peroxidase (HRP), 4',6-diamidino-2-phenylindol-2HCl (DAPI) and Fast Blue (FB) differ in retrograde labeling of striato-nigral neurons. After a 24 h survival, injection of DAPI into the ventral tegmentum labeled numerous cells throughout the neostriatum, whereas an identical amount of HRP ...

journal_title：Neuroscience letters

authors： Frotscher M,Wagner A,Misgeld U

更新日期：1983-07-29 00:00:00

abstract：:Spinal motor neurones in the adult mouse were labelled retrogradely with both True Blue and horseradish peroxidase (HRP). Using the cell sorter, motor neurones were separated on the basis of cell size and the intensity of True Blue fluorescence. Cultures of the sorted cells were then prepared and the motor neurones we...

journal_title：Neuroscience letters

authors： Eagleson KL,Bennett MR

更新日期：1983-07-29 00:00:00

abstract：:A hybridoma cell line secreting a monoclonal antibody against catalytic subunits of acetylcholinesterase in the electric organ of Narke japonica has been obtained by using a mouse immunized with the nerve terminal membranes prepared from the electric organ of Narke japonica. This monoclonal antibody (Nj-501) reacted w...

journal_title：Neuroscience letters

authors： Abe T,Sakai M,Saisu H

更新日期：1983-07-15 00:00:00

abstract：:The photoactivable compound phenylazide interacts reversibly with the frog's olfactory epithelium when delivered as an olfactory stimulus. Its application together with UV irradiation resulted in a differential reduction of the responses (electro-olfactogram) to several odorants. It was found that this chemical modifi...

journal_title：Neuroscience letters

authors： Delaleu JC,Holley A

更新日期：1983-06-30 00:00:00

abstract：:Antidromic action potentials were recorded from rat paraventricular nucleus (PVN) and supraoptic nucleus neurons following electrical stimulation of the pituitary stalk. Increases in stimulation frequency to 10 or 20 Hz caused progressive increases in antidromic latency and, often, failure of the antidromic potential ...

journal_title：Neuroscience letters

authors： Pittman QJ

更新日期：1983-06-30 00:00:00

abstract：:Four substance P (SP) antagonists were tested on anaesthetized rats, by injecting 8 microgram amounts into the spinal cord (T8-T9), and by observing their effects on the hypothalamo-neurohypophysial responses to a presumably painful stimulus, the superfusion of the hepatic portal vein with 1 microM bradykinin. Only tw...

journal_title：Neuroscience letters

authors： Stoppini L,Baertschi AJ,Mathison R,Barja F

更新日期：1983-06-30 00:00:00

abstract：:Somatostatin (SRIF) release from rat hypothalamus was investigated in vitro with a perifusion system. Glucagon (1 microM) and high potassium concentrations (56 mM) stimulated SRIF release in a calcium-dependent manner. Pretreatment of the rat with cysteamine (30 mg/100 g body weight, 7 h earlier) significantly reduced...

journal_title：Neuroscience letters

authors： Shimatsu A,Kato Y,Matsushita N,Ohta H,Kabayama Y,Imura H

更新日期：1983-06-30 00:00:00

abstract：:Transient retinal fibers to the inferior colliculus were found in newborn albino rats. After horseradish peroxidase injection into the vitreous cavity of rats of 1-3 days of age, anterogradely-labeled retinal fibers were traced through the superior colliculus to the inferior colliculus. These retinal fibers to the inf...

journal_title：Neuroscience letters

authors： Kato T

更新日期：1983-05-27 00:00:00

abstract：:The chronic administration of phencyclidine-HCl (PCP-HCl), 10 mg/kg, for 6-7 days resulted in a significant increase in the striatal methionine-enkephalin level, although acute administration induced no change of methionine-enkephalin level in this area. The methionine-enkephalin levels in other areas investigated, i....

journal_title：Neuroscience letters

authors： Nabeshima T,Hiramatsu M,Amano M,Furukawa H,Kameyama T

更新日期：1983-05-27 00:00:00

abstract：:The activities of RNA-dependent DNA polymerase and DNA-dependent DNA polymerase were measured in hippocampus of fast and slow learning Wistar rats. The RNA-dependent DNA polymerase activity in the hippocampus of fast learning rats exceeds two-fold that in the slow learning ones, while the rates of the DNA-dependent DN...

journal_title：Neuroscience letters

authors： Salganik RI,Parvez H,Tomsons VP,Shumskaya IA

更新日期：1983-04-29 00:00:00

abstract：:Kainic acid rapidly suppresses both ON- and OFF-visually evoked responses in the tectum after injection into the vitreous of chicken eyes. One week after injection the OFF-responses were still suppressed, while ON-responses were detected of similar magnitude but of simplified form to those of control eyes. It is sugge...

journal_title：Neuroscience letters

authors： Dvorak DR,Morgan IG

更新日期：1983-04-29 00:00:00

abstract：:A major action of adenosine is the induction of profound behavioral inactivity. 6-(4-Nitrobenzyl)-thioinosine (NBI) and 6-(2-hydroxy-5-nitrobenzyl)-thioguanosine (NBG) have been shown to inhibit adenosine uptake. To investigate the possible synergism between exogenous ligand and reuptake inhibition, mice were treated ...

journal_title：Neuroscience letters

authors： Crawley JN,Patel J,Marangos PJ

更新日期：1983-04-11 00:00:00

abstract：:Double retrograde axonal tracers (horseradish peroxidase, (HRP) and [3H]apo-HRP) have been used to study the distribution of labeled cells in the cat claustrum. Paired injections were made into different fields of the visual cortical areas. Although the areas of distribution of single-labeled claustral neurons from di...

journal_title：Neuroscience letters

authors： Norita M

更新日期：1983-03-28 00:00:00

abstract：:The modification of tuning properties in the cochlea has been studied by means of tuning curves from auditory nerve fibers in kittens of various ages. Comparison of tuning curves of three characteristic frequencies (CF) shows that the tuning of high CF units tends to approach adult values by the end of the second post...

journal_title：Neuroscience letters

authors： Romand R

更新日期：1983-03-14 00:00:00

abstract：:Previous electron spin resonance (ESR) studies employing a protein-specific spin label have suggested an alteration in membrane proteins in erythrocytes in Huntington's disease (HD). Recently, Beverstock and Pearson [4] have published the results of an ESR study not confirming our findings. In the present communicatio...

journal_title：Neuroscience letters

authors： Butterfield DA,Markesbery WR

更新日期：1983-02-21 00:00:00

abstract：:Striatal neurons containing acetylcholine and somatostatin were examined using a pharmacohistochemical procedure for acetylcholinesterase and NADPH-diaphorase histochemistry respectively. The use of these two histochemical procedures allowed both cholinergic and somatostatin cells to be visualized simultaneously in si...

journal_title：Neuroscience letters

authors： Vincent SR,Staines WA,Fibiger HC

更新日期：1983-02-21 00:00:00

abstract：:Using high performance liquid chromatography (HPLC) and electrochemical detection, serotonin and its precursor 5-hydroxytryptophan (5-HTP) were identified in crude perchloric acid extracts from bovine cornea. In addition, dopamine, noradrenaline and adrenaline were identified. Through the use of immunohistochemical pr...

journal_title：Neuroscience letters

authors： Osborne NN

更新日期：1983-01-31 00:00:00

abstract：:Two electrophysiologically distinct cell types were found with intracellular recordings for the first time in an in vitro preparation of the olfactory epithelium of the salamander, Ambystoma tigrinum. Intracellular recordings showed that Type I cells did not discharge action potentials but had high resting membrane po...

journal_title：Neuroscience letters

authors： Masukawa LM,Kauer JS,Shepherd GM

更新日期：1983-01-31 00:00:00

abstract：:Specific (nerve growth factor, NGF) and non-specific (serum albumin, BSA) uptake followed by retrograde axonal transport was studied in the sciatic nerves of normal (C57BL/6J) and dystrophic (dy2J/dy2J) mice. In the dystrophic mouse there was a significant decrease in the amount of NGF transported to dorsal root gangl...

journal_title：Neuroscience letters

authors： Rutherford PS,Boegman RJ

更新日期：1982-12-31 00:00:00

abstract：:Using antibodies to somatostatin in combination with the avidin-biotin immunohistochemical method, the laminar distribution and morphology of somatostatin-like (SOM-L) immunoreactive cells have been studied in the hippocampal formation of the rat. SOM-L positive cells are present throughout the longitudinal axis of th...

journal_title：Neuroscience letters

authors： Köhler C,Chan-Palay V

更新日期：1982-12-31 00:00:00

abstract：:Most of the phasically occurring periods of rapid eye movements (REMs) of active sleep are accompanied by enhanced suppression of somatomotor activity; however, during some of the REM episodes there are muscular twitches and jerks. The membrane potential changes underlying these motor processes were examined by record...

journal_title：Neuroscience letters

authors： Chase MH,Morales FR

更新日期：1982-12-30 00:00:00

abstract：:Bilateral, radiofrequency destruction of the hypothalamic paraventricular nucleus resulted in a pronounced depression in levels of immunoreactive (ir-) vasopressin (VP) in the medulla-pons of rats. The contents of ir-dynorphin1-17 (DYN), ir-DYN1-8 and ir-alpha-neo-endorphin (alpha-NE) therein were not, in contrast, af...

journal_title：Neuroscience letters

authors： Millan MH,Millan MJ,Herz A

更新日期：1982-12-30 00:00:00

abstract：:The soluble fraction of rat brain cortex yielded an antioxidant factor that inhibits the autoxidation of ascorbic acid at physiological pH. The measurements were based on spectrophotometric detection of ascorbic acid at 265 nm in a physiological salt solution of the Krebs-Ringer type, pH 7.4, or in sodium phosphate bu...

journal_title：Neuroscience letters

authors： Kovachich GB,Mishra OP

更新日期：1982-12-23 00:00:00

abstract：:Angiotensin II-sensitive neurons in the brain of spontaneously hypertensive rats (SHR-sp) and of Wistar Kyoto rats (WKY) treated with the angiotensin-converting enzyme inhibitor Captopril were investigated for possible differences at receptor sites. Furthermore, the concentrations of angiotensinogen and renin were mea...

journal_title：Neuroscience letters

authors： Felix D,Schelling P

更新日期：1982-12-23 00:00:00

abstract：:A highly significant endogenous lateral asymmetry in striatal dopamine (D2) receptors was found utilizing the binding of [3H]spiroperidol (0.6 nM) to homogenates prepared from the left and the right striata of male rats individually assayed. The mean level of binding was 23% greater in left than in right striatum, whi...

journal_title：Neuroscience letters

authors： Schneider LH,Murphy RB,Coons EE

更新日期：1982-12-13 00:00:00

abstract：:The presence of serotonin (5-HT)-like immunoreactivity has been detected in ganglionar cell bodies of the nodose ganglia of the cat, using the peroxidase-antiperoxidase immunohistochemical method, applied to sections of ganglia previously embedded in paraffin. The antibodies were raised in rabbits following injection ...

journal_title：Neuroscience letters

authors： Gaudin-Chazal G,Portalier P,Barrit MC,Puizillout JJ

更新日期：1982-11-30 00:00:00

abstract：:Localizations of thalamic relay neurons of vibrissae, common fur of the muzzle and head, as well as those projecting to the cortical vibrissal field in mice with vibrissae coagulated at birth, have been studied by retrograde transport of peroxydase. The tracer was injected in the corresponding cortical areas. In coagu...

journal_title：Neuroscience letters

authors： Verney C,Farkas-Bargeton E,Verley R

更新日期：1982-10-23 00:00:00

abstract：:RMI 12330A dose-dependently inhibits cAMP accumulation induced by PGE2 in guinea-pig superior cervical ganglion (SCG). Norepinephrine (NE) is unable to modify cAMP concentration in the same preparation. On the other hand, both PGE2 and NE block the firing discharge of guinea-pig SCG neurons elicited by electrical stim...

journal_title：Neuroscience letters

authors： Borasio PG,Ferretti ME,Biondi C,Trevisani A

更新日期：1982-10-08 00:00:00

abstract：:Local cerebral glucose utilization (LCGU) was measured during spontaneous waking and slow wave sleep (SWS) by an adaptation of the [14C]deoxyglucose method to the free moving cat. In awake animals heterogeneous rates of LCGU were observed throughout the brain with values extending from 8 mumol x 100 g-1 x min-1 for wh...

journal_title：Neuroscience letters

authors： Petitjean F,Seguin S,Des Rosiers MH,Salvert D,Buda C,Janin M,Debilly G,Jouvet M,Bobillier P

更新日期：1982-09-20 00:00:00

abstract：:The cells of origin of the brainstem projection to the caudate-putamen (CP) were examined in the albino rat by the use of two fluorescent retrograde tracers. Nuclear yellow was injected into the CP of one hemisphere and granular blue was injected into the contralateral CP. Retrogradely labeled cells were studied in th...

journal_title：Neuroscience letters

authors： Loughlin SE,Fallon JH

更新日期：1982-09-20 00:00:00

abstract：:Rat pineal glands incubated in vitro with 10 or 100 microM norepinephrine (NE) released 51% and 415% more prostaglandin E2 (PGE2) to the medium than in the absence of NE. Phentolamine (10 microM) prevented fully the effect of NE at both concentrations, whereas propranolol failed to affect it significantly. After super...

journal_title：Neuroscience letters

authors： Ritta MN,Cardinali DP

更新日期：1982-08-31 00:00:00

abstract：:We have used Lucifer Yellow for histological tracing of displaced amacrine cells within the ganglion cell layer (GCL) during the embryonic development of the chicken retina. Incubating whole eyes in the dye leads to bright staining of all displaced amacrine cells, whereas ganglion cells and glial cells are not stained...

journal_title：Neuroscience letters

authors： Layer PG,Vollmer G

更新日期：1982-08-16 00:00:00

abstract：:The irreversible labeling by [3H]flunitrazepam of three proteins with apparent molecular weights of 51,000 (P51), 55,000 (P55) and 59,000 (P59) was investigated using hippocampal membranes isolated from rats at various timepoints after birth. The present results indicate that [3H]flunitrazepam predominantly labels P55...

journal_title：Neuroscience letters

authors： Sieghart W,Mayer A

更新日期：1982-07-20 00:00:00

abstract：:We studied the influence of caffeine treatment (50 mg/kg for 3 doses) on catecholamine utilization and adrenergic receptor binding in female rats. Caffeine enhanced the reduction in forebrain norepinephrine levels following alpha-methyl-p-tyrosine without altering the reduction in dopamine levels. Caffeine reduced the...

journal_title：Neuroscience letters

authors： Goldberg MR,Curatolo PW,Tung CS,Robertson D

更新日期：1982-07-20 00:00:00

abstract：:The role of dopamine (DA) in the rat locus coeruleus (LC) was investigated by determining the levels of 3,4-dihydroxyphenylacetic acid (DOPAC), DA and noradrenaline (NA) in the LC after pharmacological treatments by pargyline, haloperidol, 6-hydroxydopamine (6-OHDA) and desmethylimipramine (DMI). The DA, DOPAC and NA ...

journal_title：Neuroscience letters

authors： Milon H,McRae-Degueurce A

更新日期：1982-06-30 00:00:00

abstract：:Horseradish peroxidase (HRP) was injected within the thalamic ventrobasal complex of 14 cats. The aim was to ascertain whether the periaqueductal grey matter (PAG) sends fibres to this complex. Retrogradely labelled cells were found within the PAG following HRP delivery either in the nucleus ventralis posterolateralis...

journal_title：Neuroscience letters

authors： Barbaresi P,Conti F,Manzoni T

更新日期：1982-06-30 00:00:00

abstract：:Three populations of opiate binding sites (mu, delta and kappa) could be distinguished by displacement studies with the mu-agonist (D)-Ala2-MePhe4-Glyol5-enkephalin and the kappa-agonist [3H](-)-bremazocine in brain membranes of different species. Whereas brain membranes from pig or guinea-pig and human cortical membr...

journal_title：Neuroscience letters

authors： Maurer R

更新日期：1982-06-30 00:00:00

abstract：:The somatosensory projection to the striatum of the rat was investigated by electrophysiological mapping. Fifty-five units were encountered that responded to specific forms of stimulation delivered to particular parts of the body. Units that responded to stimuli delivered to the hindlimb, scrotum and tail were found i...

journal_title：Neuroscience letters

authors： Richards CD,Taylor DC

更新日期：1982-06-30 00:00:00